Title of article - Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats.
Abstract
Propofol (2, 6-diisopropylphenol) is an intravenous anesthetic that is commonly used for the general anesthesia. It is well known that the spinal cord is one of the working targets of general anesthesia including propofol. However, there is a lack of investigation of the effects of propofol on spinal dorsal horn which is important for the sensory transmission of nociceptive signals. The objective of this study was to investigate the effects of increasing dosage of propofol on the release of glutamate (Glu), γ-aminobutyric acid (GABA) and glycine (Gly) in the spinal dorsal horn.
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Department of Anesthesiology, Chinese People Liberation Army (PLA) General Hospital, Beijing 100853, China.
Details of Journal for Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats.
Journal Title - Iranian journal of basic medical sciences
ISSN - 2008-3866
Volume - 18
Issue - 8
Publish date - 2015-Aug
Language - eng
Country - Iran
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