Title of article - Interaction between HSP 70 and iNOS in skeletal muscle injury and repair.
Abstract
Muscle injuries are frequently occurred in various sports. The biological process and mechanism of muscle repair after injury are well known through the many studies. This study aimed at presenting heat shock protein and nitric oxide synthase are to respond to muscle damage and repair. This section discusses the results obtained through many articles. Heat shock proteins (HSPs) are considered to play an essential role in protecting cells from damage, preparing them to survive on new environmental challenges. In addition, exercise-induced changes such as heat shock, oxidative, metabolic, muscular, and cytokine stress seem to be responsible for the HSP response to exercise. Also, inducible nitric oxide synthase (iNOS) generates nitric oxide (NO) for prolonged period and causes pathophysiological effects. Furthermore, iNOS is involved in processes such as cell injury, wound repair, embryogenesis, tissue differentiation, and suppression of tumorigenesis. In conclusion, the inhibition of HSP 70 on caspase-3 and apoptosis is associated with its inhibition on iNOS that leads to less NO production.
CLICK HERE for Full article Click button above to go to original article link with complete article details for Interaction between HSP 70 and iNOS in skeletal muscle injury and repair.
Please CLICK HERE to discuss with us on facebook about this article.
Click below for Details of research Institute
School of Exercise & Sport Science, College of Natural Sciences, University of Ulsan, Ulsan, Korea.
Details of Journal for Interaction between HSP 70 and iNOS in skeletal muscle injury and repair.
Journal Title - Journal of exercise rehabilitation
ISSN - 2288-176X
Volume - 11
Issue - 5
Publish date - 2015-Oct
Language - eng
Country - Korea (South)
No comments:
Post a Comment