Title of article - Current Approach to the Management of Eosinophilic Esophagitis in Adults.
Abstract
Eosinophilic esophagitis (EoE) is an increasingly diagnosed, immune-mediated disease characterized by inflammation of the esophagus in both children and adult, causing significant morbidity. Adults typically present with dysphagia and a history of food impaction. Diagnosis should be considered in patients with histological evidence of eosinophilia (≥15 eosinophils per high-power field) on esophageal biopsy. More recently, it has been observed that a significant percentage of patients with esophageal eosinophilia respond both clinically and histologically to PPI therapy. This disorder has been named PPI-responsive esophageal eosinophilia (PPI-REE). Recent studies suggest that patients with PPI-REE have similar clinical and endoscopic features of patients with EoE. Specifically, both PPI-REE and EoE patients have a strong disposition to allergy compared to patients without eosinophilia. As such, PPI-REE may represent a subset or variant of EoE. Effective treatment of EoE requires a multidisciplinary approach with gastroenterologists, pathologists, allergists, and nutritionists. Treatments include elimination and elemental diets, topical glucocorticoids (fluticasone and budesonide), and endoscopic dilation.
CLICK HERE for Full article Click button above to go to original article link with complete article details for Current Approach to the Management of Eosinophilic Esophagitis in Adults.
Please CLICK HERE to discuss with us on facebook about this article.
Click below for Details of research Institute
Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Details of Journal for Current Approach to the Management of Eosinophilic Esophagitis in Adults.
Journal Title - Current treatment options in gastroenterology
ISSN - 1092-8472
Volume - 13
Issue - 4
Publish date - 2015-Dec
Language - eng
Country - United States
No comments:
Post a Comment