Title of article - Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria.
Abstract
Alkaptonuria (AKU) clinical manifestations resemble severe arthritis. The Suitability of Nitisinone in Alkaptonuria 1 (SONIA 1) study is a dose-finding trial for nitisinone treatment of AKU patients. We tested a panel of serum and urinary biomarkers reflecting extracellular matrix remodelling (ECMR) of cartilage, bone and connective tissue in SONIA 1 patients to identify non-invasive and diagnostic biomarkers of tissue turnover in AKU.
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Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark.
Details of Journal for Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria.
Journal Title - JIMD reports
ISSN - 2192-8304
Volume - 24
Issue - 0
Publish date - 2015-
Language - eng
Country - Germany
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